Marc J Palm (AKA Swellzombie) lives and works as a cartoonist/illustrator in Seattle. Marc has been drawing for 20+ years where comics and film have always been the biggest influences. Marc's comics are at http://swellzombie.blogspot.
As far as this concept goes... The radioactive spider that bit Peter ends up mutating him into this human sized spider. He tries his hardest to maintain a normal teenage human appearance by using his special make-up effects hobby to mold masks of his old face and hands. He's also learned to manipulate the 8 limbs in order to look like 4 within the limits of long sleeves and pants.
In this story, there's no choice whether or not he's Spider-man. Peter has to decide how much he wants to keep up a human facade. He's torn between his deep human connections with friends/family and then the freedom of fighting crime as a wild "mut-animal".